MEG 21 with Supplamine® began as a tangent while researching new treatments for diabetes-related complications. While the research focused on treating and preventing kidney disease and blindness in diabetic patients, Dr. Annette M. Tobia, Ph.D., realized that, when topically applied, many of these same compounds used to treat diabetics could also be used to treat and prevent visible signs of aging in the skin. After more than seven independent trials showed remarkable results, MEG 21 with Supplamine® was launched as an innovative professional skincare line.

MEG 21 with Supplamine® is a comprehensive skincare line that revolves around the theory of glycation. The simplest way to explain the glycation theory is that it proposes that glucose (sugar) binds to proteins and lipids in the skin, causing oxidative stress. Oxidative stress, in turn, causes premature aging in the skin. MEG 21 with Supplamine® is designed to help reduce stress, while plumping and firming fine lines and wrinkles, evening the tone, reducing redness, brightening dark spots and improving the texture.